Vaccine Development Process Map

Welcome to the Vaccine Development Process Map

This process map was developed by the UK Vaccine R&D Network, to show key stages in vaccine development up to Phase III clinical trials. The Network is supporting vaccine R&D against some of the world's deadliest outbreak infectious diseases, and this process map is intended to support Network members in understanding key stages in development and where bottlenecks could potentially delay progress.

The Network has given careful consideration to the definition of bottlenecks associated with vaccine R&D, and whilst many stages could be flagged as “bottlenecks” by broader definition that they are rate-limiting steps, we have chosen to specifically identify those processes and stages which:

  1. reduce the capacity and speed of the whole chain due to limited/sub-optimal capacity or capability within current systems, but
  2. which could potentially be rectified or improved through the efforts of the UK community (including academia, industry, and national actors)

The UK Vaccine R&D Network has also produced a summary of key points to guide decision making in the context of an emergency response to an epidemic or pandemic.

Select this link to be taken to the Prioritisation of Vaccine Development decision making resource.

The UK Vaccine R&D Network has carried out case studies to highlight where bottlenecks in vaccine development occurs in response to an outbreak.

Select this link to be taken to the case studies.

These resources are intended to be overall guides and the UK Vaccine R&D Network takes no responsibility for how this may be used in individual vaccine R&D projects.

We welcome feedback for improvements. If you have feedback please email us at vaccinology@headoffice.mrc.ac.uk.

Last updated 10th August 2017

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